Pharmaceutical manufacturers with United States Food and Drug Administration-approved prescription drugs sold in or into Texas with any prescription drugs costing $100 or more for a one-month supply as outlined in Chapter 441, §441.002 (c) are required to submit a manufacturer activity report.

The manufacturer activity report is a list of every drug that has lost patent exclusivity and/or received U.S. FDA approval in the last three calendar years. It also includes the manufacturer’s R&D costs.

Last updated: 08/14/2020

Search by brand/generic name
Manufacturer Change type Change year NDC 11 Trade Name Generic Name R and D cost
ACADIA Pharmaceuticals Inc. A 2016 63090034030 NUPLAZID pimavanserin $240,385,000
ACADIA Pharmaceuticals Inc. A 2016 63090010030 NUPLAZID pimavanserin $240,385,000
B. Braun Medical Inc. A 2019 264937988 Bupivacaine HCl 0.75% in Dextrose 8.25% Injection USP Bupivacaine HCl 0.75% in Dextrose 8.25% Injection USP $55,260,000
B. Braun Medical Inc. A 2019 264450005 Plenamine 15% Amino Acids Injection $55,260,000
B. Braun Medical Inc. A 2018 264937688 1% Lidocaine Injection 1% Lidocaine Injection $55,260,000
B. Braun Medical Inc. A 2018 264780090 0.9% Sodium Chloride Injection USP 0.9% Sodium Chloride Injection USP $55,260,000
B. Braun Medical Inc. A 2018 264780001 0.9% Sodium Chloride Injection USP 0.9% Sodium Chloride Injection USP $55,260,000
B. Braun Medical Inc. A 2018 264450000 Plenamine 15% Amino Acids Injection $55,260,000
Endo Pharmaceuticals L 2019 52244003060 Striant testosterone buccal system $130,732,000
Endo Pharmaceuticals L 2018 63481018316 FORTESTA testosterone $130,732,000
ENDO PHARMACEUTICALS INC A 2020 Doxepin Doxepin $130,732,000
ENDO PHARMACEUTICALS INC A 2020 Naloxone Hydrochloride Naloxone Hydrochloride $130,732,000
ENDO PHARMACEUTICALS INC A 2020 73611030010 Qwo collagenase clostridium histolyticum aaes $130,732,000
ENDO PHARMACEUTICALS INC A 2020 73611030005 Qwo collagenase clostridium histolyticum aaes $130,732,000
ENDO PHARMACEUTICALS INC A 2020 00254101019 Diazoxide Diazoxide $130,732,000